Pires, M. L. and Dreyer, G.


Revista do Hospital das Clinicas da Faculdade de Medicina de São Paulo , 48(4): 175-182, 1993.


Strongyloidiasis is a worldwide parasitic disease and of great importance in Brazil . Among the diverse species of Strongyloides, only the following are of importance to man: S. stercoralis, S. fulleborni and S. fullerboni –like. Eventhough S. stercoralis is an intestinal helminth, strongyloidiasis is a systemic infection that can affect, beside the gastrointestinal tract, lungs, CNS, liver and billiary tract, pancreas, genitourinary tract and skin. The great majority of cases are asymptomatic, having a chronic and benign course. Among the symptomatic subjects, the gastrointestinal and pulmonary symptoms prevail. For unknown reasons, strongyloides infection may result in severe, disseminated disease. Immunosuppressive therapy was identified as an important risk factor for disseminated illness. Diagnosing strongyloidiasis may be difficult, and even though the parasitological stool examination is the most used diagnostic test, sometimes larvae cannot be identified. Immunodiagnosis is not yet accessible for routine usage and is still a subject of research. Thiabendazole remains the dug of choice for treatment of strongyloidiasis, but other drugs, such as ivermectin, have been used. The purpose of this paper was to review the important aspects of the S. stercoralis infection in man.

Descriptors: Strongyloidiasis. Strongyloides stercoralis.