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Dreyer, G. & Coelho, G.

LYMPHATIC FILARIASIS: A POTENTIALLY ERADICABLE DISEASE.

Cadernos de Saúde Pública, 13(3):537-543, 1997.

ABSTRACT

The recent demonstration that single-dose ivermectin, diethylcarbamazine, or a combination
of these drugs can profoundly suppress Wuchereria bancrofti and Brugia malayi microfilaremia
for periods of six months to two years has led to renewed hope that transmission can be interrupted and lymphatic filariasis eradicated. Based in part on the availability of these new
chemotherapeutic tools, the International Task Force for Disease Eradication recently identified
lymphatic filariasis as one of the few diseases that could potentially be eradicated. Thus, control
programs based on mass treatment (whether supplemented or not by vector control) have begun
to be implemented in some endemic areas.We provide a brief review of available anti-filarial
drugs for use in humans, including their tolerance and efficacy.